New at Your Skin Solution · Skin Care Guide · Updated July 2026
SkinCeuticals P-TIOX Cream is a wrinkle- and pore-modulating peptide moisturizer that helps visibly smooth deep-set lines and reduce the look of pores — without needles. It completes the needle-free P-TIOX routine that began with the P-TIOX serum. Here's what you need to know.
What is P-TIOX Cream?
A corrective moisturizer targeting two concerns at once: deep-set expression wrinkles and visible pores. Its patent-pending formula pairs 10% Myrixin™ with 2% tripeptide technology — inspired by the way neuromodulators relax the look of contraction lines, delivered in a daily cream. The "micro-melting" texture gives 24-hour hydration with no greasy finish, and it suits normal, combination, oily, and sensitive skin.
- Helps visibly reduce deep-set wrinkles and pores — including concerns injections alone don't target
- Boosts hydration by +94% in just 1 hour*
- Physician-tested to complement neuromodulator injections
- Fragrance-free, silicone-free, paraben-free
Key ingredients
- 10% Myrixin™ + 2% tripeptide — helps visibly reduce contraction lines and even static wrinkles visible at rest
- 1% Crystalide Micropeptide — the "glass skin peptide," for a dewy, luminous finish
- 5% niacinamide + LHA — visibly refines pores and smooths texture
- Zinc PCA — helps balance sebum for a clearer-looking complexion
Clinically measured results
In SkinCeuticals' 12-week clinical study (77 women and men, ages 23–45, all skin tones, dermatologist-evaluated), P-TIOX Cream showed: −17% forehead wrinkles, −10% nasolabial folds, −21% pore size, and +24% smoothness.*
*Average results, 12-week single-centre clinical study on subjects with mild to moderate wrinkles, fine lines, visible pores and rough texture. Individual results may vary.
P-TIOX Serum vs. P-TIOX Cream
They're teammates, not substitutes: the serum is your concentrated treatment step; the cream is your moisturizer with corrective peptides built in. Together they deliver advanced glass-skin radiance in as little as 1 week.
| P-TIOX Serum | P-TIOX Cream | |
|---|---|---|
| Focus | Expression wrinkles, texture, radiance | Deep-set wrinkles, pores, 24h hydration |
| Key technology | Amplified peptide complex + niacinamide, PHA | 10% Myrixin™ + 2% tripeptide, niacinamide + LHA |
| Routine step | Correct (after antioxidant serum) | Moisturize (last corrective step) |
How to use it
Twice daily, after your corrective serums, press a small amount evenly into skin on the face, neck, and around the eyes. In the morning, always finish with sunscreen.
Explore the full lineup on our SkinCeuticals brand page.
FAQ
Is P-TIOX Cream suitable for sensitive skin?
Yes — it's clinically tested on all skin types and tones, including sensitive skin, and is fragrance-free, silicone-free, and paraben-free.
Can I use it with neuromodulator injections?
Yes. It's physician-tested to complement neuromodulator injections and helps visibly reduce deep-set wrinkles and pores that injections alone don't target.
Do I need both the serum and the cream?
Each works alone, but they're designed as a pair — the serum targets expression lines and radiance, the cream adds deep-set wrinkle correction, pore refinement, and hydration.
Is P-TIOX Cream available in Canada?
Yes. Your Skin Solution is an authorized Canadian retailer of SkinCeuticals — every jar is guaranteed authentic, with free shipping on orders over $100 and samples in every order.
Where to buy P-TIOX Cream in Canada
P-TIOX Cream (48 ml, $225.00) is available now at Your Skin Solution, Canada's authorized online retailer of medical-grade skincare.