Three skinbetter science products are built for the things a retinoid does not fully answer: expression lines, the look of firmness, and the neck. InterFuse Treatment Cream FACE & NECK ($210) is the peptide cream. InterFuse Intensive Treatment LINES ($210) is the targeted treatment for crow's feet, forehead and smile lines. Techno Neck Perfecting Cream ($250) is the one made only for the neck and chest. Here is what each does, how they overlap, and the order to use them in.
Quick answers
- What is InterFuse?
- skinbetter science's patented delivery technology, designed to help large ingredients such as peptides and hyaluronic acid get where they need to go in the skin. Two products in our range carry it.
- InterFuse Face & Neck or Techno Neck for my neck?
- Techno Neck if the neck is the main concern. InterFuse Face & Neck if you want one peptide cream that covers the face and takes in the neck.
- What is LINES for?
- Expression lines specifically: crow's feet, forehead, upper lip and smile lines. It is applied to those areas only, as the first step, morning and evening.
- Do these replace AlphaRet?
- No. They work alongside it. AlphaRet is the retinoid; these are peptide and hyaluronic acid products used in the same routine.
- Morning or night?
- All three are directed for morning and evening.
What InterFuse technology is
Peptides and hyaluronic acid are large molecules, and the skin's outer layer is built to keep large molecules out. That is the problem most peptide creams quietly have: the ingredient on the label is real, but a good deal of it stays on the surface. InterFuse is skinbetter science's patented delivery system, engineered, in the brand's words, to help high-performance ingredients that are traditionally resistant to topical application reach the skin more efficiently.
It is a delivery technology, not an active in itself. What it carries is what matters, and in the two InterFuse products we stock that is a blend of peptides, hyaluronic acid in several molecular sizes, and a vitamin C derivative. Techno Neck, the third product in this guide, is not an InterFuse product. It belongs here because it answers the same question, the look of firmness and texture, on the one area a face cream is least likely to reach properly.
The short version. AlphaRet is skinbetter's answer to lines and tone across the whole face. These three are what you add when a specific area needs more: expression lines, sagging, or the neck.
The three products
InterFuse Treatment
Cream FACE & NECK
InterFuse Intensive
Treatment LINES
Techno Neck
Perfecting Cream
InterFuse Treatment Cream FACE & NECK
InterFuse Treatment Cream FACE & NECK is the everyday peptide cream in the range. skinbetter positions it for the look of sagging, lines and wrinkles, and for the loss of firmness and elasticity that comes with age. The formula carries a blend of what the brand calls messenger peptides and neuro-calming peptides, Mediterranean olive extract, glycerin and shea butter, all delivered through InterFuse. It is used morning and evening across the face, neck and chest, and in practice it doubles as a moisturizer for normal, combination and dry skin. If you want to add peptides to a skinbetter routine with a single product, this is it.
InterFuse Intensive Treatment LINES
InterFuse Intensive Treatment LINES is not a face cream. It is a targeted treatment for expression lines, the ones formed by movement: crow's feet, the forehead, the upper lip and the smile lines that run from the nose to the mouth. skinbetter's phrase for it is that it relaxes the look of expression lines. The formula is built around hyaluronic acid in five molecular sizes, two neuro-calming peptides, and a complex of amino acids, messenger peptides and a stable vitamin C derivative. The directions are specific and worth following exactly: a thin layer on clean, dry skin, to those areas only, as the first step in the routine, morning and evening. The 15 ml size looks small until you realise it is only ever going on four small areas.
Techno Neck Perfecting Cream
Techno Neck Perfecting Cream is the one product in the range made for the neck and chest and nothing else. skinbetter positions it for the look of laxity, crepiness, dryness and texture on the neck, which is thinner skin than the face, has fewer oil glands, and is the area most people forget until it starts to show. The formula carries peptide complexes built on arginine, adenosine and carnosine, heptapeptide-7, hydrolysed hyaluronic acid, niacinamide, a vitamin C derivative and green tea extract. It is applied as a thin layer to the neck and chest, morning and evening, and the 50 ml jar reflects that it is covering a larger area than a face cream does.
Side by side
| Product | Built for | Where it goes | What is in it | Use |
|---|---|---|---|---|
| InterFuse Treatment Cream FACE & NECK$210 · 30 ml | The look of sagging, lines, wrinkles and lost firmness across the whole face | Face, neck and chest | Messenger and neuro-calming peptides, olive extract, shea butter. InterFuse delivery | Morning and evening, as your cream |
| InterFuse Intensive Treatment LINES$210 · 15 ml | The look of expression lines specifically | Crow's feet, forehead, upper lip and smile lines only | Hyaluronic acid in five sizes, two neuro-calming peptides, amino acids, messenger peptides, vitamin C derivative. InterFuse delivery | Thin layer, first step, morning and evening |
| Techno Neck Perfecting Cream$250 · 50 ml | The look of laxity, crepiness, dryness and texture on the neck | Neck and chest only | Arginine, adenosine and carnosine peptide complexes, heptapeptide-7, hyaluronic acid, niacinamide, vitamin C derivative, green tea. Not an InterFuse product | Thin layer, morning and evening |
All three are dermatologist tested, non-comedogenic, and formulated without parabens, fragrance or dyes. All three directions call for sunscreen during the day.
Face & Neck cream or Techno Neck
This is the question that stalls most people, because one product has the word neck in its name and the other is the neck product. The honest answer is that they are not competing for the same job.
InterFuse Treatment Cream FACE & NECK is a face cream whose directions extend to the neck and chest. If you are already going to buy a peptide cream for your face, the neck comes along with it, and for many people that is enough. Techno Neck Perfecting Cream is formulated for neck skin specifically, with a jar sized for it, and it is the product to buy when the neck is the reason you are shopping: crepiness, a loss of definition along the jaw, texture across the chest.
The rule of thumb. If your face is the priority and the neck is a secondary thought, InterFuse Face & Neck covers both. If you would describe your neck as the concern, Techno Neck, and use whatever face cream you already like. Using both is reasonable if you want the peptide cream on the face and the dedicated product below the jaw, but it is not necessary.
Which one is right for you
| Your concern | Buy | Why |
|---|---|---|
| General loss of firmness, whole face | InterFuse Face & Neck | The all-over peptide cream. Doubles as your moisturizer |
| Crow's feet, forehead lines, lines around the mouth | InterFuse LINES | Made for exactly those areas, and nothing else |
| Crepey or slack neck, texture on the chest | Techno Neck | The only product in the range built for that skin |
| Firmness on the face and lines around the eyes and mouth | InterFuse LINES and InterFuse Face & Neck | LINES first on the targeted areas, the cream over everything |
| Already happy with your moisturizer, want peptides for the neck | Techno Neck | Adds the neck step without changing anything on the face |
| Lines under the eyes rather than at the corners | EyeMax AlphaRet | LINES is for crow's feet. The under-eye is EyeMax territory |
The order to use them in
The rule across skinbetter's range is thin before thick, targeted before all-over. With these three products that gives you:
- Cleanse. Skin should be clean and dry before LINES goes on.
- InterFuse LINES, if you use it, on crow's feet, forehead, upper lip and smile lines only. The brand's directions make this the first step, before serums.
- Serum, if you use one. Mystro morning and evening, or Alto in the morning.
- At night, AlphaRet if it is in your routine.
- InterFuse Face & Neck as your cream, over everything above, taking it down the neck and chest. Or your usual moisturizer if you are not using it.
- Techno Neck on the neck and chest, if you use it. A thin layer.
- Morning only: broad-spectrum sunscreen, over the face and the neck. Every one of these products directs it.
How they fit with AlphaRet
None of these replace a retinoid, and skinbetter does not position them that way. AlphaRet works on lines, tone and texture over months by way of renewal. The peptide products work on the appearance of firmness and on specific lines by a different route, and they are used in the same routine rather than instead of it.
Two pairings are worth knowing. skinbetter's own neck routine puts Techno Neck alongside AlphaRet Overnight Cream, which tells you the brand sees the neck as somewhere the retinoid belongs too, with Techno Neck carrying the daytime and the texture side. And InterFuse LINES sits comfortably under AlphaRet at night because it goes on first, to small areas, and has absorbed before the retinoid arrives. If you are new to AlphaRet, our AlphaRet guide covers which of the three to start with, and our skinbetter routine guide shows where all of this fits around the four core steps.
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Shop skinbetter scienceFrequently asked questions
What is InterFuse technology?
InterFuse is skinbetter science's patented delivery technology. It is designed to help large ingredients that are traditionally difficult to deliver topically, such as peptides and hyaluronic acid, reach the skin more efficiently. InterFuse Treatment Cream FACE & NECK and InterFuse Intensive Treatment LINES both use it.
What is the difference between InterFuse Face & Neck and InterFuse LINES?
InterFuse Treatment Cream FACE & NECK is an all-over peptide cream for the look of firmness, lines and wrinkles, used across the face, neck and chest as your moisturizer. InterFuse Intensive Treatment LINES is a targeted treatment for expression lines, applied only to crow's feet, forehead, upper lip and smile lines, as the first step in the routine.
Should I use InterFuse Face & Neck or Techno Neck on my neck?
Techno Neck Perfecting Cream if the neck is your main concern, since it is formulated specifically for neck and chest skin. InterFuse Treatment Cream FACE & NECK if you want one peptide cream that covers the face and extends to the neck. Using both is fine but not necessary.
Is Techno Neck an InterFuse product?
No. Techno Neck Perfecting Cream does not use InterFuse delivery technology. It is a separate skinbetter science formula built on peptide complexes, hyaluronic acid, niacinamide and a vitamin C derivative, made for the neck and chest.
Where exactly do I apply InterFuse LINES?
InterFuse Intensive Treatment LINES goes on crow's feet, the forehead, the upper lip and the smile lines from nose to mouth, as a thin layer on clean, dry skin. It is the first step in the routine, morning and evening, followed by the rest of your skinbetter products.
Do InterFuse or Techno Neck replace AlphaRet?
No. InterFuse Face & Neck, InterFuse LINES and Techno Neck are peptide and hyaluronic acid products, not retinoids. They are used in the same routine as AlphaRet, not instead of it. skinbetter science's own neck routine pairs Techno Neck with AlphaRet Overnight Cream.
Can I use InterFuse Face & Neck as my moisturizer?
Yes. InterFuse Treatment Cream FACE & NECK is a cream applied morning and evening to the face, neck and chest, and for normal, combination and dry skin it works as the moisturizer step. Very dry skin may want a richer cream such as Trio Luxe over it at night.
Is InterFuse LINES an eye cream?
Not in the usual sense. InterFuse Intensive Treatment LINES is applied to crow's feet at the outer corners of the eyes, but it is not directed for the under-eye area. For the under-eye, skinbetter science's EyeMax AlphaRet Overnight Cream and Instant Effect Gel EYE are the products made for that skin.
Where can I buy InterFuse and Techno Neck in Canada?
skinbetter science is dispensed through clinics and authorized online retailers only. Your Skin Solution is an authorized Canadian retailer of skinbetter science, including InterFuse Treatment Cream FACE & NECK, InterFuse Intensive Treatment LINES and Techno Neck Perfecting Cream, with free shipping on orders over $99 within Canada.
Product descriptions, directions and technology names are as published by skinbetter science. Prices are in Canadian dollars, current as of 29 September 2026, and may change. Descriptions refer to visible, cosmetic change. Individual results vary. This article is general information, not medical advice. Speak with your dermatologist or skincare professional about what suits your skin.